OrthoNet

Adamantinoma

- 1o bone tumor with predilection for tibial diaphysis presenting during early adulthood

Signs & Symptoms:
- painful masses with variable symptom duration ranging from few months to few years

Xrays:
- well-circumscribed, eccentric, lytic lesions of tibial diaphysis
- may be multicystic lesion with surrounding sclerosis
- expansion of bone +/- intact cortex but no periosteal reaction

Histology:
- wide variety of histologic appearances
- basaloid pattern composed of groups of cells which peripherally have palisading epithelial cells
- hypocellular, poorly organized, fibrous connective tissue between islands of epithelial cells

Treatment:
- wide excision (limb salvage vs amputation)
- 20-25% metastasize to lungs